Winemaking variables and techniques are known to affect the phenolic composition of red
wines. This review surveys the current literature on the impact of processing and fermentation …

There remains a high unmet medical need for a safe oral therapy for thrombotic disorders.
The serine protease factor Xa (fXa), with its central role in the coagulation cascade, is among …

Compound 1 was identified by high throughput screening as a novel, potent, non-amidine
factor Xa inhibitor with good selectivity against thrombin and trypsin. A series of modifications …

… Karna L. Sacchi … The major diastereomer generated from the reaction with the (R,R) ligand
gives α-diketone 3, the result of a matched attack by the nucleophilic enol on intermediate …

A series of thiophene-containing non-amidine factor Xa inhibitors is described. Simple
methyl-substituted thiophene analogs were relatively weak inhibitors. However, introduction of …

Compound 1 was identified by high throughput screening as a novel PAI-1 inhibitor. Optimization
of the B and C-segments of 1 resulted in a series of structurally simplified compounds …

… against Karnal bunt (Tilletia indica) were used to investigate the role of three members of
cystatin gene family in growth stage dependent immunity in wheat (Triticum aestivum L.). Three …

… animal house located at NDRI, Karnal. The samples from the remaining species were collected
from the commercial slaughter houses located in Karnal. The IAEC approved the current …

In order to understand the intricate mechanism of differential immunity against Karnal bunt (KB),
basal levels of carotenoids, abscisic acid (ABA), total protease and protease inhibitor …